{"id":1958,"date":"2023-03-27T11:14:43","date_gmt":"2023-03-27T06:44:43","guid":{"rendered":"https:\/\/nhiso.com\/shop\/?post_type=product&#038;p=1958"},"modified":"2024-03-16T21:46:12","modified_gmt":"2024-03-16T18:16:12","slug":"nccls-h22-p-1984","status":"publish","type":"product","link":"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/","title":{"rendered":"NCCLS H22-P-1984"},"content":{"rendered":"<p>Histochemical Method for Leukocyte Alkaline Phosphatase<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neutrophilic leukocytes contain an alkaline phosphomonesterase with variable activity in normal subjects and in patients with hematological and nonhematological disorders. Leukocyte alkaline phosphatase is a well established term and thus will be used, although we recognize that in the peripheral blood the enzyme is virtually restricted to neutrophil polymorphonuclear cells. There is no relationship between leukocyte alkaline phosphatase and serum alkaline phosphatase. The function of leukocyte alkaline phosphatase is still unknown, but normal leukocyte alkaline phosphatase depends on an intact pituitary adrenal axis. Clinical interest in leukocyte alkaline phosphatase was stimulated initially by the observation that the leukocytes of patients with chronic granulocytic leukemia usually had low levels of enzymatic activity in contrast to high values seen in leukocytosis of other disorders. Quantitative methods of assay are available but are not practical. Semiquantitative assay by a variety of azo dye histochemical methods has made determination of leukocyte alkaline phosphatase a widely used clinical test. This document describes a standard histochemical method which should serve as a benchmark.<\/p>\n","protected":false},"featured_media":1960,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_cat":[26],"product_tag":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCCLS H22-P-1984 - \u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/\" \/>\n<meta property=\"og:locale\" content=\"fa_IR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCCLS H22-P-1984 - \u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\" \/>\n<meta property=\"og:description\" content=\"Neutrophilic leukocytes contain an alkaline phosphomonesterase with variable activity in normal subjects and in patients with hematological and nonhematological disorders. Leukocyte alkaline phosphatase is a well established term and thus will be used, although we recognize that in the peripheral blood the enzyme is virtually restricted to neutrophil polymorphonuclear cells. There is no relationship between leukocyte alkaline phosphatase and serum alkaline phosphatase. The function of leukocyte alkaline phosphatase is still unknown, but normal leukocyte alkaline phosphatase depends on an intact pituitary adrenal axis. Clinical interest in leukocyte alkaline phosphatase was stimulated initially by the observation that the leukocytes of patients with chronic granulocytic leukemia usually had low levels of enzymatic activity in contrast to high values seen in leukocytosis of other disorders. Quantitative methods of assay are available but are not practical. Semiquantitative assay by a variety of azo dye histochemical methods has made determination of leukocyte alkaline phosphatase a widely used clinical test. This document describes a standard histochemical method which should serve as a benchmark.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-16T18:16:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nhiso.com\/shop\/wp-content\/uploads\/2023\/03\/40.png\" \/>\n\t<meta property=\"og:image:width\" content=\"504\" \/>\n\t<meta property=\"og:image:height\" content=\"217\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/\",\"url\":\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/\",\"name\":\"NCCLS H22-P-1984 - \u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\",\"isPartOf\":{\"@id\":\"https:\/\/nhiso.com\/shop\/#website\"},\"datePublished\":\"2023-03-27T06:44:43+00:00\",\"dateModified\":\"2024-03-16T18:16:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/#breadcrumb\"},\"inLanguage\":\"fa-IR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u062e\u0627\u0646\u0647\",\"item\":\"https:\/\/nhiso.com\/shop\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u0641\u0631\u0648\u0634\u06af\u0627\u0647\",\"item\":\"https:\/\/nhiso.com\/shop\/shop\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"NCCLS H22-P-1984\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nhiso.com\/shop\/#website\",\"url\":\"https:\/\/nhiso.com\/shop\/\",\"name\":\"\u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\",\"description\":\"\u0641\u0631\u0648\u0634 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0628\u06cc\u0646 \u0627\u0644\u0645\u0644\u0644\u06cc\",\"publisher\":{\"@id\":\"https:\/\/nhiso.com\/shop\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nhiso.com\/shop\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fa-IR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nhiso.com\/shop\/#organization\",\"name\":\"\u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\",\"url\":\"https:\/\/nhiso.com\/shop\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fa-IR\",\"@id\":\"https:\/\/nhiso.com\/shop\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/nhiso.com\/shop\/wp-content\/uploads\/2021\/12\/MQD-Logo.jpeg\",\"contentUrl\":\"https:\/\/nhiso.com\/shop\/wp-content\/uploads\/2021\/12\/MQD-Logo.jpeg\",\"width\":565,\"height\":409,\"caption\":\"\u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a\"},\"image\":{\"@id\":\"https:\/\/nhiso.com\/shop\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NCCLS H22-P-1984 - \u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nhiso.com\/shop\/product\/nccls-h22-p-1984\/","og_locale":"fa_IR","og_type":"article","og_title":"NCCLS H22-P-1984 - \u0641\u0631\u0648\u0634\u06af\u0627\u0647 \u062a\u0648\u0633\u0639\u0647 \u06a9\u06cc\u0641\u06cc\u062a","og_description":"Neutrophilic leukocytes contain an alkaline phosphomonesterase with variable activity in normal subjects and in patients with hematological and nonhematological disorders. Leukocyte alkaline phosphatase is a well established term and thus will be used, although we recognize that in the peripheral blood the enzyme is virtually restricted to neutrophil polymorphonuclear cells. There is no relationship between leukocyte alkaline phosphatase and serum alkaline phosphatase. The function of leukocyte alkaline phosphatase is still unknown, but normal leukocyte alkaline phosphatase depends on an intact pituitary adrenal axis. Clinical interest in leukocyte alkaline phosphatase was stimulated initially by the observation that the leukocytes of patients with chronic granulocytic leukemia usually had low levels of enzymatic activity in contrast to high values seen in leukocytosis of other disorders. Quantitative methods of assay are available but are not practical. Semiquantitative assay by a variety of azo dye histochemical methods has made determination of leukocyte alkaline phosphatase a widely used clinical test. 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