Immunoglobulin and T-Cell Receptor Gene Rearrangement Assays; Approved Guideline\u2014Second Edition<\/p>\n
MM2-A2 Vol. 22 No. 12<\/p>\n","protected":false},"excerpt":{"rendered":"
Assays that detect monoclonal rearrangement of immunoglobulin or T-cell receptor genes are useful adjunct methods in the diagnosis of leukemia or lymphoma. Prudent clinical use requires a thorough understanding of the sensitivity and technical artifacts associated with these methods, together with the ability to prudently weigh the results. NCCLS document MM2\u2014Immunoglobulin and T-Cell Receptor Gene Rearrangement Assays helps laboratorians perform and interpret gene rearrangement assays. It includes indications for gene rearrangement analysis and acceptable methods for specimen collection, transport, and processing. Also included are recommendations for assessing specimen adequacy, as well as technical methods for conducting gene rearrangement assays, including information on sensitivity, specificity, controls, and test interpretation. Quality assurance procedures are included throughout the document. NCCLS. Immunoglobulin and T-Cell Receptor Gene Rearrangement Assays; Approved Guideline\u2014 Second Edition. NCCLS document MM2-A2 (ISBN 1-56238-466-X). NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2002.<\/p>\n","protected":false},"featured_media":1802,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_cat":[26],"product_tag":[],"yoast_head":"\n